Epigentics and Genomic Instability

reproduced for study purposes. Please see also “Poverty linked to epigenetic changes and mental illness -Impoverished adolescents acquire DNA marks, brain changes and depression over time.” Sara Reardon 24 May 2016 for a clear introduction to epigenetics and genomic instability as a background. Environment and stressors affects how genes express and how cells read and respond to gene expression. A marked gene need not be a “damaged gene”, however processes due to environment may alter the expression of a gene. The consequences of this may be many. One outcome may be disease. A marked, undamaged, gene may be transmissible to offspring if it is a germ cell (sperm, egg).

Selected pages from http://www.melodi-online.eu/doc/13_chakraborty_melodi-2012_web.pdf Epigenetic Events and Radiation Exposure, Ranajit Chakraborty, PhD Center for Computational Genomics, Institute of Applied Genetics,
Department of Forensic and Investigative Genetics, Univ. North
Texas Health Science Center, Fort Worth, Texas 76107, USA. nvited Talk given at the MELODY-2012 Workshop at Helsinki, Finland, on September 13, 2012

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