Radiation-induced chromosome aberrations in nuclear-dockyard workers. Evans et. al. Nature, 277, 531 – 534 (15 February 1979)

http://www.nature.com/nature/journal/v277/n5697/abs/277531a0.html

Nature 277, 531 – 534 (15 February 1979); doi:10.1038/277531a0

Radiation-induced chromosome aberrations in nuclear-dockyard workers

H. J. Evans, K. E. Buckton, G. E. Hamilton & A. Carothers

Medical Research Council, Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh, UK

The incidence of chromosome aberrations in peripheral blood lymphocytes of 197 dockyard workers has been followed over a 10-yr period. These workers were exposed to mixed neutronγ radiation during the refuelling of nuclear reactors, but most exposures were below the internationally accepted maximum permissible level of 5 rem per yr. There was a significant increase in chromosome damage with increasing exposure, aberration frequency was a linear function of dose and was influenced by age and time of blood sampling after exposure.

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References
1. Kucerova, M., Anderson, A. J. B., Buckton, K. E. & Evans, H. J. Int. J. Radiat. Biol. 21, 389–396 (1972).
2. Scott, D., Sharpe, H., Batchelor, A. L., Evans, H. J. & Papworth, D. G. Mutat. Res. 8, 367–381 (1969).
3. Carrano, A. V. Radiat. Res. 63, 403–421 (1975).
4. Lloyd, D. C., Purrott, R. J., Dolphin, G. W. & Edwards, A. A. Int. J. Radiat. Biol. 29, 169–182 (1976).
5. Buckton, K. E. et al. Int. J. Radiat. Biol. 19, 369–378 (1971).
6. Dolphin, G. W., Lloyd, D. C. & Purrott, R. J. Hlth Phys. 25, 7–15 (1973).
7. Evans, H. J. & Lloyd, D. C. (eds) Mutagen-induced Chromosome Damage in Man (University Press, Edinburgh, 1978).
8. Buckton, K. E., Dolphin, G. W. & McLean, A. S. in Human Radiation Cytogenetics (eds Evans, H. J., Court Brown, W. M. & McLean, A. S.) 174–182 (North-Holland, Amsterdam, 1967).
9. Evans, H. J. & O’Riordan, M. L. Mutat. Res. 31, 135–148 (1975).
10. Galloway, S. M. & Buckton, K. E. Cytogenet. Cell Genet. 20, 78–95 (1978).
11. Fitzgerald, P. H. Humangenetik 28, 153–158 (1975).
12. Bochkov, N. P., Kozlov, V. M., Pilsov, R. A. & Sevenkaev, A. V. Genetika 4, 93–98 (1968).
13. Buckton, K. E., Hamilton, G. E., Paton, L. & Langlands, A. O. in Mutagen-induced Chromosome Damage in Man (eds Evans, H. J. & Lloyd, D. C.) 142–150 (University Press, Edinburgh, 1978).
14. Sasaki, M. S. & Tonomura, A. Jap. J. hum. Genet. 14, 81–92 (1969).
15. Evans, H. J. & Adams, A. in Advances in Radiation Biology Vol. 1 (eds Duplan, J. F. & Chapiro, A) 335–348 (Gordon and Breach, New York, 1973).
16. Najarian, T. & Colton, R. Lancet i, 1018–1020 (1978).
17. Torrey, L. New Scient. 77, 726–727 (1978).
18. Mancuso, T. F., Stewart, A. & Kneale, G. Hlth Phys. 33, 369–385 (1977).
19. Kneale, G., Stewart, A. & Mancuso, T. in IAEA Int. Symp. Late Biol. Effects of Ionising Radiations, Vienna, March 1978 (in the press).
20. Mole, R. H. Lancet i, 1155–1156 (1978).
21. Reissland, J. A. & Dolphin, G. W. Lancet i, 1156–1157 (1978).
22. Marks, S., Gilbert, E. S. & Breitenstein, B. D. in IAEA Int. Symp. Late Biol. Effects of Ionising Radiations, Vienna, March 1978 (in the press).
23. Reissland, J.A. National Radiological Protection Board Report No. R79 (H.M. Stationery Office, London, 1978).
24. Reissland, J. A., Kay, P. & Creasey, F. L. in National Radiological Protection Board Annual Research and Development Report 1977, 228 (H.M. Stationery Office, London, 1978).

© 1979 Nature Publishing Group

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